Research Progress

[15-01-2020]The mini-ferritin-AIE system may be useful in developing novel functional probes for tumour nanot...

In a recent study, the research group led by Prof. LI Feng in Wuhan Institute of Virology of the Chinese Academy of Sciences used red AIE PS molecules to prepare stable AIE nanodots for cell imaging and PDT via a simple method with a highly negatively charged mini-ferritin protein as the scaffold. The as-prepared protein-AIE nanodots showed strong fluorescence emission and efficient singlet oxy...

[14-01-2020]Scientists clarify HIV entry into resting CD4 T cells

In a recent study by the research group led by Prof. CUI Zongqiang in Wuhan Institute of Virology of the Chinese Academy of Sciences, using QD-based single-virus imaging, the scientists tracked the dynamic processes of HIV fusion and interactions with the cortical actin in resting CD4 T cells.

[29-10-2019]Scientists provide new insights into LASV GP-host interactions

In a recent study by the research group led by Prof. XIAO Gengfu in Wuhan Institute of Virology of the Chinese Academy of Sciences, a comprehensive LASV GP interactome was characterized, and further study revealed that STT3B-dependent N-glycosylation was preferentially required by arenavirus GPs and critical for virus infectivity.

[10-07-2019]Two immunogen candidates have potential utility for neutralizing antibody selection and vaccine d...

Zika virus (ZIKV), as a re-emerging viral pathogen, belongs to the Flaviviridae family including dengue virus (DENV), West Nile virus (WNV), Japanese encephalitis virus (JEV), yellow fever virus (YFV), and tick borne encephalitic virus (TBEV). It can be transmitted by Aedes mosquitoe and cause severe neurological diseases including Guillain-Barre Syndrome (GBS) in the adult, and congenital Zika...